Paliperidone is one of the primary active metabolites that can be found
in the antipsychotic treatment risperidone (also known as
Risperdal). Though extensive research has yet to define what the specific mechanism
of action, or the biochemical interaction of the drug substance, of the
paliperidone drug is, scientists do believe that its effects are nearly
identical to that of the risperidone drug. Invega was the original name
given to the paliperidone drug, and was approved by the Food and Drug
Administration (FDA) in 2006 as another option for schizophrenia treatments
as well as bipolar mania. In 2009, the FDA also approved its usage in
order to specifically treat schizoaffective disorder.
All of these above conditions relate to certain social and emotional behavior
disorders, and paliperidone was established as a means of treating these
conditions. It is also very common that doctors will use this prescription
as an off-label, similar to risperidone, in order to treat other conditions
such as Asperger syndrome or autism.
Invega Sustenna is the injectable form of paliperidone treatment, and was
approved by the FDA in 2009 as a long-acting injectable form of the prescription.
In the U.S. the patient is given a monthly dosage every 28 days by their
physician in the form of an injection with 75 mg, which has the equivalent
of taking paliperidone orally every day in 6 mg dosages. The oral Invega
dosage of 6 mg compares to a risperidone prescription a patient would
take daily of 2 or 3 mg. When a patient is given Invega Sustenna, it is
injected deep into the muscle tissue.
Prolactin in Invega Sustenna
The hormone prolactin is an active ingredient in all risperidone medications.
This is the hormone that causes women to produce milk during a pregnancy,
and also causes women to grow breasts during puberty. When prolactin is
injected into the body in Invega Sustenna, it can encourage breast growth
in both males and females.
In male patients, this is a condition called
Those with this condition will develop large breasts and may even lactate
as a result. Some men have required breast reduction surgery or a mastectomy
to remove the unwanted growths on their body. This serious symptom of
risperidone medications like Invega Sustenna can emotionally and psychologically
damaging as well. Males who are forced to undergo the embarrassment of
breast growth often fall into unstable psychological conditions as a result.
The shame of the situation, as well as the discomfort and pain of a mastectomy
can be astronomical.
Warnings & Side Effects of Invega Sustenna
Invega Sustenna has been compared by doctors to having the similar, if
not identical, effects as risperidone. As a result, patients are cautioned
with many possible side effects associated with this form of behavior
and mood treatment medication. While there are warnings today about the
possibility of certain side effects, many male victims have suffered severely
by taking these treatments without receiving the knowledge of a particular
concern regarding the prolactin hormone that is effected in the body.
One of the biggest concerns with both paliperidone and risperidone is
the fact that due to the significantly increased prolactin levels, particularly
in male patients of all age, they may experience unwanted breast tissue
growth and breast milk, among many other possible health concerns.
According to the Invega Sustenna website, some of the side effects of the
medication include missing menstrual periods, lactating from the breasts,
and the development of breasts in men. Currently, a popular respiridone
medication called Risperdal is the subject of various lawsuits because
of arguments about the labeling of the drug. Many men who have suffered
from gynecomastia say that they could have been spared the embarrassment
and shame of their situation if the packets of Risperdal had clearer warnings
about the breast growth side effect.
Common side effects of this drug may include, but are not limited to:
- Gynecomastia and galactorrhea;
- Drowsiness, lightheadedness, dizziness, weight gain;
- Muscle spasms, restlessness, fever, sore throat, irregular heartbeat, seizures;
- Uncontrollable muscle movements in the face, lips, tongue, mouth, arms
or legs (tardive dyskinesia condition)
- Neuroleptic malignant syndrome
Representation in Invega Sustenna Lawsuits
If you are suffering from gynecomastia because you took Invega Sustenna
or another risperidone medication with the prolactin hormone, then you
may have the right to seek compensation from the drug maker. Invega Sustenna
is a Janssen medication by Johnson & Johnson, the same company that
also manufactures Risperdal. All pharmaceutical companies are required
to post the side effects of their medicine blatantly on the packaging
so that it will serve as a warning to individuals that are receiving injections.
If a company is not clear in their labeling, or circumvents the FDA's
oversight then you may be able to seek compensation. Hire a
personal injury attorney at Arnold & Itkin today.