Risperidone & HPG Axis Dysfunction
Risperidone has been linked to dysfunction of the endocrine glands that are collectively referred to as the HPG axis. Risperidone, also referred to as Risperdal, has been the cause of many lawsuits due to children / teenagers who have suffered adverse side effects caused by the drug. If you are a victim of risperidone, call our drug injury attorneys.
Arnold & Itkin recently fought for a young man who suffered from the side effects of Risperdal. We secured a $76.6 million verdict—the largest Risperdal verdict to date by more than 2000 percent. Do not hesitate to discuss your needs with our firm in a free case consultation. Call (888) 493-1629 today, or fill out our short online form.
What Is Risperidone?
Risperidone is used to treat antipsychotics, such as schizophrenia. Some generic risperidone drugs are used to treat autism in pediatric cases. Risperidone is an atypical antipsychotic drug and is considered a dopamine antagonist. This drug was originally approved for use in cases of schizophrenia back in 1993, but this was limited to use in adults.
In 2003, the drug was also approved for short-term treatment of mixed and manic states that were associated with bipolar disorder. Three years later, children and adults who were autistic could use the drug to reduce irritability. It wasn't until August 2007 that the FDA determined risperidone could be used in in youths between the ages of 13-17 as it was the only drug that was on the market for this purpose. Later, it was approved for children 10-17 who had been diagnosed with bipolar disorder.
Off-label versions of the drug are used to treat a variety of conditions such as:
- Obsessive-compulsive disorder
- Treatment-resistant depression
- Tourette syndrome
- Eating disorders
- Behavior disorders in children
- Acute intoxication
What Are the Dangers of Risperidone?
Reports have proven that risperidone comes with some serious risks and can create embarrassing and devastating side effects. The medicine has been linked with HPG Axis Dysfunction, which stands for hypothalamic-pituary-gonadal axis dysfunction. In this condition, the pituary gland, gonads, or hypothalamus in the body are tampered with in a way that causes them to stop working correctly. Together, the three endocrine glands that make up the HPG axis operate to develop and regulate the reproductive systems and the immune system.
In some cases, risperidone can cause the body to release serum prolactin from the pituary gland. While adults normally don't suffer side effects from this process, children with developing bodies are at more of a risk to an illness or injury. When the prolactin levels remain elevated after taking risperidone, this can result in delayed sexual maturation and reduced bone growth. As well, prolactin's main function in the body is to cause breast enlargement during pregnancy. Per The Journal of Family Practice, this is also supposed to create lactation during pregnancy. Unfortunately, there are times that risperidone will cause a male child to develop breasts and even lactate.
Symptoms of HPG Axis
When prolactin keeps the HGP Axis from working, it can cause a variety of symptoms. These are seen in children, rather than in adults who take the medication. When children take the medicine and prolactin is secreted within the body it can result in one of the following conditions:
- Decreased Libido
- Erectile Dysfunction
- Bone Density Loss
- Breast Enlargement
- Breast Engorgement
As a result, many children may fail to have a natural maturation during puberty, or may have an increased risk of benign breast tumors. HPG axis dysfunction has also been known to cause reduced bone density.
Suffering from HPG Axis Dysfunction? If you have developed a condition because of taking risperidone or a drug that is related to risperidone, then you need assistance from a defective drug attorney to seek compensation for your injuries. You should not be forced to suffer the adverse effects of HPG axis dysfunction without due compensation. Contact our firm to discuss your case.